Any paint, or body work product that is catalized ( has hardener added ) is extremely dangerous. Hardener has an ingredient called isocyanate, or cyanide. Once inhailed it never leaves your body, and continues to build up with more exposure. Primers, paint and body fillers all have this chemical. Even after the products mentioned have dried, they are still dangerous when sanded and made ingestable or inhailed. It can also be absorbed through the skin and particularly through the eyes. The eyes are second only to inhilation as the most effective way to gain exposure to these chemicals. You should at the very least be using a full body paint suit and fresh charcoal filter mask when spraying paint and primer. ( charcoal masks last an average of 8 hours and should be stored in a sealed plastic bag when not in use to prolong there life.)
When sanding body filler, putty, or paint you should always wear a good quality mask to limit exposure by inhilation. Some of the signs of exposer are headaches, nausia, and shaking, because these chemicals affect the nervouse system. I still work in this industry, but I now have to be very careful about my exposure, and have become over sensitized. I cannot paint or prime without using a fresh air system and full body suit. Although I can't say with certainty it is quite likely that my level of exposure will have adverse effects on my life expectancy. So, be careful guys, and take care of yourselves. When those fumes are making you happy it's all fun and games untill the headaches start.
Just my two cents worth.