if you are topping out at 45 with a 4.10 gear I wonder if you dont have other problems. a 1:1 top gear (you should have 4 gears in a 1 ton floor shift) and 4.10 rear end should do 45mph at about 2000 rpm, your engine should have more legs that that.
a colorado 4x4 rear is wide enough and has the right centerbore and bolt pattern to fit your wheels, but will be 3.73 and that will only drop your rpm about 250 rpm. without an overdrive top gear you will want to get closer to a 2.73 rear gear, that will give you 62 mph at the same engine speed, thats better than a 0.76 overdrive from an s10. you can find a 2.73 in a lot of 2wd chevy trucks the same year as your k5 axle and can likely swap your 6 lug axles and drums to the axle. a 2.73 will make first gear almost usable too haha.
a colorado 4x4 rear is wide enough and has the right centerbore and bolt pattern to fit your wheels, but will be 3.73 and that will only drop your rpm about 250 rpm. without an overdrive top gear you will want to get closer to a 2.73 rear gear, that will give you 62 mph at the same engine speed, thats better than a 0.76 overdrive from an s10. you can find a 2.73 in a lot of 2wd chevy trucks the same year as your k5 axle and can likely swap your 6 lug axles and drums to the axle. a 2.73 will make first gear almost usable too haha.